منابع مشابه
Pediatric Germ Cell Tumors: A Developmental Perspective
Germ cell tumors (GCTs) arising in infants, children, and adolescents present a set of special challenges. GCTs make up about 3% of malignancies in children aged 0-18 and nearly 15% of cancers in adolescents. Epidemiologic and molecular evidence suggests that GCTs in young children likely represent a distinct biologic group as compared to GCTs of older adolescents and adults. Despite this diffe...
متن کاملHematologic disorders associated with primary mediastinal nonseminomatous germ cell tumors.
BACKGROUND The association between primary germ cell tumors of the mediastinum (the space between the lung pleura that contains the heart and other chest viscera) and hematologic malignancies has been described by retrospective analysis of patients treated at individual clinical centers. To better characterize the risk of hematologic disorders in patients with extragonadal germ cell tumors and ...
متن کاملExuberant Vasculoconnective Component in Mediastinal Mixed Germ Cell Tumors
We aimed to evaluate the histologic components of primary mediastinal mixed germ cell tumors. A total of 221 patients diagnosed with a mediastinal germ cell tumor (GCT) were retrospectively reviewed. Among them, 14 patients underwent surgical resection after chemotherapy and 8 patients were diagnosed with mixed GCT, who were then selected for further evaluation. Clinical chart review and histol...
متن کاملPediatric malignant germ cell tumors show characteristic transcriptome profiles.
Malignant germ cell tumors (GCT) of childhood are rare and heterogeneous neoplasms thought to arise from primordial germ cells. They vary substantially in their natural history and show important clinical differences from their adult counterparts. To address the biological basis for these observations, we have undertaken a comprehensive analysis of global gene expression patterns in pediatric m...
متن کاملPediatric Germ Cell Tumors; A 10-year Experience
OBJECTIVE The aim of this study was to evaluate the outcome of germ cell tumors in patients admitted to our center during a ten year period. METHODS In a retrospective descriptive study, patients with the pathological diagnosis of germ cell tumor (GCT) were included. All records were evaluated and patients followed by personal visit in clinic or phone call. Data regarding age, sex, tumor site...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Mediastinum
سال: 2019
ISSN: 2522-6711
DOI: 10.21037/med.2019.07.02